 | Tim Curry | Long John Silver |
 | Billy Connolly | Billy Bones |
 | Jennifer Saunders | Mrs. Bluveridge |
 | Kevin Bishop | Jim Hawkins |
 | Dave Goelz | The Great Gonzo / Dr. Bunsen Honeydew / Waldorf / Mudwell the Mudbunny / Zoot (voice) |
 | Steve Whitmire | Kermit the Frog / Rizzo the Rat / Beaker (voice) |
 | Jerry Nelson | Statler / Blind Pew / Mad Monty / Floyd Pepper / Lew Zealand / Tomato / Pirate / Skulls / Trelawney's Butler / Screaming Cat (voice) |
 | Kevin Clash | Bad Polly / Black Dog / Spa'am / Chicken / Miss Piggy (assistant) / Fozzie Bear (assistant) / Sam the Eagle (assistant) / Animal (assistant) / Walleyed Pike / Monkey / Pirate / Real Old Tom (voice) |
 | Bill Barretta | Clueless Morgan / Swedish Chef / Blind Pew (hands) / Pirate / Pig / Skulls (voice) |
 | Frank Oz | Miss Piggy / Fozzie Bear / Sam the Eagle / Animal (voice) |
 | John Henson | Sweetums (voice) |
| Danny Blackner | Short Stack Stevens |
| Peter Geeves | Black Eyed Pea |
| Harry Jones | Easy Pete |
| David J. Nicholls | Captain Flint |
 | Frederick Warder | Calico Jerry |
| Nigel Plaskitt | Additional Muppet Performer |
 | Louise Gold | Female Tourist Rat / Rat Tour Guide (voice) |
| John Eccleston | Additional Muppet Performer |
| Simon Buckley | Additional Muppet Performer |
| Katherine Smee | Additional Muppet Performer |
| Andrew James Spooner | Additional Muppet Performer |
| Robbie Barnett | Additional Muppet Performer |
| James Barton | Additional Muppet Performer |
| Michael Bayliss | Additional Muppet Performer |
| Charles Broughton | Additional Muppet Performer |
| David Bulbeck | Additional Muppet Performer |
 | Dave Chapman | Additional Muppet Performer |
| Marcus Clarke | Additional Muppet Performer |
| Sue Dacre | Additional Muppet Performer |
| Taylor David | Additional Muppet Performer |
| Geoff Felix | Additional Muppet Performer |
| Mike Gallant | Additional Muppet Performer |
| Pat Garrett | Additional Muppet Performer |
| Barnaby Harrison | Additional Muppet Performer |
| Mark Jefferis | Additional Muppet Performer |
| William Todd-Jones | Additional Muppet Performer |
| Robin Kingsland | Additional Muppet Performer |
| Steven Kynman | Additional Muppet Performer |
| Christopher Leith | Additional Muppet Performer |
| Anthony Lymboura | Additional Muppet Performer |
| Mark Mansfield | Additional Muppet Performer |
| Joan Morris | Additional Muppet Performer |
| Rebecca Nagan | Additional Muppet Performer |
| Margaret O'Flaherty | Additional Muppet Performer |
| Angie Passmore | Additional Muppet Performer |
| Peter Passmore | Additional Muppet Performer |
| Marie Phillips | Additional Muppet Performer |
 | Mike Quinn | Old Woman / Additional Muppet Performer (voice) |
| Gillie Robic | Additional Muppet Performer |
| Helena Smee | Additional Muppet Performer |
| John Thirtle | Additional Muppet Performer |
| Ian Thom | Additional Muppet Performer |
 | Heather Tobias | Additional Muppet Performer |
| Jürgen Tombers | Additional Muppet Performer |
| Ian Tregonning | Additional Muppet Performer |
| Robert Tygner | Additional Muppet Performer |
| James Vaughan | Additional Muppet Performer |
| John Wheatley | Additional Muppet Performer |
 | Victoria Willing | Additional Muppet Performer |
| Phill Woodfine | Additional Muppet Performer |
| Sarah Wright | Additional Muppet Performer |
| Paul Zerdin | Additional Muppet Performer |
| Jessica Hamilton | Big-Fat-Ugly-Bug-Faced-Baby-Eating O'Brien (uncredited) |
 | Brian Henson | (voice) (uncredited) |
 | Brian Herring | Additional Muppet Performer (uncredited) |
| Mark Alexander Todd | Boar Warrior (voice) (uncredited) |
| Peter Robbins | Additional Muppet Performer |